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. 2023 Aug 16;13:1194100. doi: 10.3389/fonc.2023.1194100

Table 4.

Pathological features of resected specimens from patients who underwent surgery.

Pathological features All
n=48 (%)
Chemotherapy
n=13 (%)
Immunotherapy
n=26 (%)
Targeted therapy
n=9 (%)
P-value
Tumor infiltrating lyphocytesa 0.631*
 <30% 33 (68.8) 9 (69.2) 19 (73.1) 5 (55.6)
 ≥30% 15 (31.3) 4 (30.8) 7 (26.9) 4 (44.4)
Dense plasma cells 0.661*
 Absent 34 (70.8) 10 (76.9) 17 (65.4) 7 (77.8)
 Present 14 (29.2) 3 (23.1) 9 (34.6) 2 (22.2)
Cholesterol clefts 0.616*
 Absent 41 (85.4) 12 (92.3) 22 (84.6) 7 (77.8)
 Present 7 (14.6) 1 (7.7) 4 (15.4) 2 (22.2)
Foamy macrophages 0.018*
 Absent 33 (68.8) 13 (100) 20 (76.9) 9 (100)
 Present 6 (12.5) 0 (0) 6 (23.1) 0 (0)
Proliferative fibrosis 0.498*
 Absent 10 (20.8) 2 (15.4) 7 (26.9) 1 (11.1)
 Present 38 (79.2) 11 (84.6) 19 (73.1) 8 (88.9)
Hyalinization 0.739*
 Absent 40 (83.3) 10 (76.9) 22 (84.6) 8 (88.9)
 Present 8 (16.7) 3 (23.1) 4 (15.4) 1 (11.1)
Giant cells 0.589*
 Absent 37 (77.1) 10 (76.9) 19 (73.1) 8 (88.9)
 Present 11 (22.9) 3 (23.1) 7 (26.9) 1 (11.1)
Necrosis 0.324
 Absent 29 (60.4) 6 (46.2) 16 (61.5) 7 (77.8)
 Present 19 (39.6) 7 (53.8) 10 (38.5) 2 (22.2)

*likelihood ratio.

The bold values denote statistical significance at P<0.05 level.