Table 1. Prediction Performance for the RF Models Using Different Features^a.

	molecular descriptor	Morgan FP	RDKit FP	MACCSkeys
log loss	0.561±0.012	0.592 ± 0.012	0.610 ± 0.009	0.592 ± 0.010
Acc	0.722±0.016	0.684 ± 0.013	0.670 ± 0.026	0.687 ± 0.019
F1 score	0.761±0.015	0.738 ± 0.020	0.724 ± 0.026	0.738 ± 0.018
AUC-ROC	0.784±0.017	0.746 ± 0.017	0.724 ± 0.022	0.742 ± 0.012

^aThe bold values represent the best scores. Prediction performance using the oral bioavailability test data set was reported in mean ± standard deviation.