Table 3. Overall performance of NeXT Dx.

	Variant	Specification
Analytic Sensitivity	Single Nucleotide Variants, AF≥5%	99.4% (CI 99.0–99.6%)
Analytic Sensitivity	Insertions/Deletions, AF≥5%	98.2% (CI 96.9–99.1%)
Analytic Sensitivity	Copy Number Alterations	98.0% (CI 93.0–99.8%)
Analytic Sensitivity	Gene Fusions	95.8% (CI 90.5–98.6%)
Analytic Specificity (PPV)	Specificity	>99%
MSI	117 Gene Loci	>99.1% Concordance
TMB	Exome Wide	0.985 Pearson correlation coefficient