Table 3. Serum levels of lipids, lipoproteins of the subjects according to CETP-TaqI genotypes.
| Variable | CETP-TaqIB Genotype | CETP-TaqIA Genotype | ||||||||||
|
|
|
|||||||||||
| B1B1 | B1B2 | B2B2 | Test for linear trenda |
A1A1 | A1A2 | Test for linear trenda |
||||||
| Men | ||||||||||||
| n | 89 | 134 | 33 | 219 | 34 | |||||||
| TC, mg/dl | 192.8 | (3.3) | 199.2 | (2.7) | 213.7 | (5.4)*† | 0.005 | 197.6 | (2.1) | 204.7 | (5.5) | 0.242 |
| HDL-C, mg/dl | 52.6 | (1.2) | 56.9 | (1.0) ‡ | 59.8 | (2.0)* | 0.003 | 55.7 | (0.8) | 56.5 | (2.1) | 0.693 |
| LDL-C, mg/dl | 115.2 | (3.2) | 117.1 | (2.6) | 128.7 | (5.3) | 0.088 | 116.9 | (2.0) | 122.8 | (5.3) | 0.312 |
| TG, mg/dl | 125.2 | (7.4) | 129.2 | (6.0) | 119.6 | (12.1) | 0.599 | 128.9 | (4.7) | 113.7 | (12.1) | 0.144 |
| TC/HDL-C ratio | 3.8 | (0.1) | 3.7 | (0.1) | 3.9 | (0.1) | 0.237 | 3.7 | (0.1) | 3.9 | (0.1) | 0.364 |
| Women | ||||||||||||
| n | 91 | 138 | 42 | 236 | 34 | |||||||
| TC, mg/dl | 207.4 | (3.4) | 210.0 | (2.7) | 219.1 | (5.0) | 0.145 | 210.6 | (2.1) | 212.3 | (5.6) | 0.826 |
| HDL-C, mg/dl | 61.4 | (1.3) | 63.7 | (1.0) | 65.7 | (1.9) | 0.138 | 63.1 | (0.8) | 64.0 | (2.1) | 0.642 |
| LDL-C, mg/dl | 126.8 | (3.2) | 127.0 | (2.6) | 133.7 | (4.7) | 0.382 | 128.1 | (2.0) | 128.8 | (5.4) | 0.968 |
| TG, mg/dl | 93.2 | (5.4) | 99.2 | (4.4) | 95.6 | (7.9) | 0.642 | 98.0 | (3.3) | 89.8 | (8.9) | 0.393 |
| TC/HDL-C ratio | 3.6 | (0.1) | 3.4 | (0.1) | 3.4 | (0.1) | 0.455 | 3.5 | (0.0) | 3.5 | (0.1) | 0.866 |
Values are Least-Squares Means (SE) adjusted for the age, log BMI, smoking, alcohol drinking, active intensity index, fasting triglyceride (except TG).
Shown at significant differences between B2B2 and B1B1 (*), B2B2 and B1B2 (†), and B2B1 and B1B1 (‡).
a The number of alleles 2 (coded as 0, 1, 2) is used as a continuous variable and tested in a GLM with the variable in the left side column as dependent variable.