Table 5. Results of multiple linear regression analysis showing the relative contributions and extents of the relation of CETP-TaqIB genotype, selected lifestyle factors, and relative parameters to serum HDL-C levels.
Dependent Variable |
Independent Variable |
Men | Women | ||||
|
|
||||||
β | PR2 | P | β | PR2 | P | ||
HDL-C, mg/dl | Age (years) | -0.1 (0.1) | 0.5 | 0.14 | 0.0 (0.1) | 0.0 | 0.75 |
Log BMI | -20.5 (6.0) | 3.0 | <0.01 | -25.0 (6.3) | 4.1 | <0.01 | |
CETP-TaqIB Genotype | |||||||
B1B1 | reference | reference | |||||
B1B2 | 4.1 (1.6) | 1.7 | <0.01 | 2.3 (1.7) | 0.6 | 0.15 | |
B2B2 | 6.9 (2.3) | 2.2 | <0.01 | 4.3 (2.3) | 1.0 | 0.06 | |
Smoking | |||||||
Nonsmokers | reference | reference | |||||
Smokers | -4.1 (1.5) | 2.0 | <0.01 | 2.8 (3.8) | 0.1 | 0.45 | |
Alcohol Drinking | |||||||
Nondrinkers | reference | reference | |||||
Drinkers | 9.6 (1.9) | 6.9 | <0.01 | 4.4 (1.6) | 2.0 | <0.01 | |
Tertiles of AII (METs) | |||||||
Tertile 1 | reference | reference | |||||
Tertile 2 | 1.6 (1.8) | 0.2 | 0.39 | 1.6 (1.8) | 0.2 | 0.37 | |
Tertile 3 | -0.1 (1.7) | 0.0 | 0.93 | 1.8 (1.9) | 0.2 | 0.36 | |
Log TG | -11.3 (1.5) | 14.0 | <0.01 | -12.0 (1.7) | 13.4 | <0.01 |
β: regression coefficient (SE); PR2: partial R2 expressed as percentages; TG: fasting triglyceride; AII: active intensity index (METs). CETP-TaqIB genotype and tertiles of AII are used as dummy variables to evaluate the effects of B1B2, B2B2, tertile 2, and tertile 3 to HDL-C, respectively.
Status of smoking or alcohol drinking is coded as 0, 1.