Table 2.
Prevalence of thrombocytopenia in patients with cancer-associated thrombosis by cancer type
| Degree of thrombocytopenia by cancer type, n (% of row) | Total CAT population | Normal >100 × 103/μL |
Grade 1 75-100 × 103/μL |
Grade 2 50-75 × 103/μL |
Grade 3 25-50 × 103/μL |
Grade 4 <25 × 103/μL |
|---|---|---|---|---|---|---|
| All cancers | 3635 (100) | 2657 (73) | 293 (8) | 269 (7) | 229 (6) | 187 (5) |
| Solid tumor | 2902 (100) | 2256 (78) | 235 (8) | 203 (7) | 156 (5) | 52 (2) |
| Gastrointestinal | 1326 (100) | 905 (68) | 144 (11) | 135 (10) | 112 (8) | 30 (2) |
| Lung / Intrathoracic | 472 (100) | 394 (83) | 30 (6) | 19 (4) | 19 (4) | 10 (2) |
| Genitourinary | 361 (100) | 313 (87) | 21 (6) | 16 (4) | 9 (2) | 2 (1) |
| Gynecologic | 222 (100) | 199 (90) | 10 (5) | 8 (4) | 2 (1) | 3 (1) |
| Breast | 204 (100) | 182 (89) | 10 (5) | 6 (3) | 6 (3) | 0 (0) |
| Other solid | 317 (100) | 263 (83) | 20 (6) | 19 (6) | 8 (3) | 7 (2) |
| Hematologic malignancy | 647 (100) | 343 (53) | 48 (7) | 61 (9) | 68 (11) | 127 (20) |
| Lymphoma | 400 (100) | 232 (58) | 32 (8) | 40 (10) | 46 (12) | 50 (13) |
| Multiple myeloma | 100 (100) | 59 (59) | 7 (7) | 8 (8) | 8 (8) | 18 (18) |
| Myeloid | 147 (100) | 52 (35) | 9 (6) | 13 (9) | 14 (10) | 59 (40) |
| Multiple cancers | 86 (100) | 58 (67) | 10 (12) | 5 (6) | 5 (6) | 8 (9) |
“Other solid” includes cancers of the nervous system, sarcoma, head and neck tumors, melanoma, and neuroendocrine tumors.