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. 2023 Aug 31;2023(8):CD013074. doi: 10.1002/14651858.CD013074.pub2

Summary of findings 3. Massage versus no intervention for people receiving dialysis.

Massage versus no intervention for people receiving dialysis
Patient or population: people receiving dialysis
Settings: multinational
Intervention: massage
Comparison: no intervention
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No. of participants
(RCTs) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
No intervention Massage
Fatigue
(PFS, FSS, VAS)
median follow‐up: 0.9 months
The mean score for fatigue ranged across control groups from 5.17 to 80.74 (PFS, FSS, or VAS scores) The mean fatigue in the intervention group was 1.06 lower than the control group (95% CI 1.47 lower to 0.65 lower) ‐‐ 657 (7) ⊕⊕⊝⊝
low1,2,3 Massage may improve fatigue compared to not intervention in people undergoing HD
Weakness Not reported Not reported ‐‐ ‐‐ ‐‐ No studies reported this outcome
Energy
(VAS)
median follow‐up: 0.9 months
The mean score for energy ranged across control groups from 18.93 to 21.97 (VAS) The mean energy in the intervention group was 4.87 more than the control group (95% CI 1.69 more to 8.06more) ‐‐ 152 (2) ⊕⊕⊝⊝
low1,3 Massage may increase energy compared to not intervention in people undergoing HD
Tiredness Not reported Not reported ‐‐ ‐‐ ‐‐ No studies reported this outcome
Exhaustion Not reported Not reported ‐‐ ‐‐ ‐‐ No studies reported this outcome
Asthenia Not reported Not reported ‐‐ ‐‐ ‐‐ No studies reported this outcome
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk Ratio; PFS: Piper Fatigue Scale; FSS: Fatigue Severity Scale; VAS: Visual Analogue Scale; HD: haemodialysis.
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1 Evidence certainty was downgraded by one level due to study limitations

2 Evidence certainty was downgraded by one level due to imprecision (Optimal Information Size (OIS)) not met and indirectness in outcome measure

3 Evidence certainty was downgraded by one level due to inconsistency