Quintiliano 2019.

Study name	Transcranial direct current stimulation in management of pain, mood, functionality, and quality of life in patients undergoing hemodialysis: a study protocol for a double‐blind controlled randomized trial
Methods	Study design RCT Duration of follow‐up: 4 weeks
Participants	Study characteristics Country: Brazil Setting: single centre Inclusion criteria Male or female aged 18 to 75 years undergoing HD with ESKD (CKD 5D2) for > 3 months, (4 hours/session) Pain‐related with a score of more than 4 (range of scores from 1 to 10) in a visual analogue scale (VAS) for > 3 months Have physical capacity to do physical evaluation and be capable of consenting to treatment and understanding study explanations and questionnaires Provide informed consent Exclusion criteria Electrical implants in the body History of epilepsy or convulsion Clinically contraindicated to receive tDCS, such as having metal embedded in their scalp or brain Psychiatric illness Pregnant women Signs of severe disease and/or indication of hospitalisation, including instability, infection, acute myocardial infarction, and stroke
Interventions	Intervention group 1 Motor cortex (M1) Intervention group 2 Dorsolateral prefrontal cortex (DLPFC) Control group Sham group Co‐interventions Not reported
Outcomes	Planned outcomes Pain: baseline, week 1 and 4 Depression: baseline, week 1 and 4 Functionality: baseline, week 1 and 4 QoL: baseline, week 1 and 4
Starting date	Not reported. Trial was registered on 2018
Contact information	Artur Quintiliano Phone: not reported Email: artur_bezerra@hotmail.com
Notes	Brazilian Clinical Trials Registry/Registro Brasileiro de Ensaios Clínicos (ensaiosclinicos.gov.br), 1111–1216‐0137. Funding: funded by the authors. Recruitment status: not reported