Table 10.

Abundance of Classes Compared Between Sexes

Class Name	No. Cells Whole Colon	% Cells Whole Colon	No. Cells Male	% Cells Male	No. Cells Female	% Cells Female
AIN1	54	2.1%	18	1.4%	36	2.8%
AIN2	71	2.7%	38	2.9%	33	2.6%
AIN3	126	4.9%	63	4.8%	63	4.9%
DIN1	41	1.6%	29	2.2%	12	0.9%
DIN2	15	0.6%	9	0.7%	6	0.5%
DIN3	127	4.9%	67	5.1%	60	4.7%
DIN4	62	2.4%	31	2.4%	31	2.4%
DIN5	52	2.0%	22	1.7%	30	2.3%
DIN6	22a	0.8%a	20a	1.5%a	2a	0.2%a
EMN1	175	6.7%	100	7.6%	75	5.8%
EMN2	192	7.4%	108	8.2%	84	6.5%
EMN3	83	3.2%	50	3.8%	33	2.6%
EMN4	328	12.6%	159	12.1%	169	13.2%
IMN1	265	10.2%	139	10.6%	126	9.8%
IMN2	110a	4.2%a	71a	5.4%a	39a	3.0%a
IMN3	392	15.1%	188	14.3%	204	15.9%
IMN4	314a	12.1%a	120a	9.2%a	194a	15.1%a
SN1	75	2.9%	34	2.6%	41	3.2%
SN2	44	1.7%	19	1.4%	25	1.9%
Misc	48	1.8%	26	2.0%	22	1.7%
Totals	2596	100.0%	1311	100.0%	1285	100.0%

Abundance of 20 classes compared between male (n = 6) and female (n = 6) patients. An omnibus chi-square test between classes and sex gave χ²₁₉ = 70.3 (P < .0001) with standard residuals indicating that 3 classes were differentially distributed; DIN6 and IMN2 were more abundant in males, whereas IMN4 was more abundant in females.

AIN, ascending interneuron; DIN, descending interneuron; EMN, excitatory motor neuron; IMN, inhibitory motor neuron; SN, sensory neuron.

^aSignificant difference (P < .05).