Table 3.
Abundance of Individual Markers in Ascending and Descending Colon Compared
| Marker | In Ascending Colon | In Descending Colon | χ21 | Corrected P |
|---|---|---|---|---|
| NOS | 52.6% | 48.3% | 4.8240 | >.05 |
| ChAT | 55.5% | 57.4% | 0.9515 | >.05 |
| 5-HT | 2.4% | 3.5% | 2.7690 | >.05 |
| SP | 7.3% | 8.6% | 1.4871 | >.05 |
| ENK | 8.2% | 11.9% | 9.8167 | .0208a |
| CGRP | 0.9% | 2.8% | 12.4154 | .0051a |
| SOM | 1.3% | 2.2% | 2.8233 | >.05 |
| Calb | 25.1% | 27.9% | 2.6564 | >.05 |
| Calret | 8.7% | 10.8% | 2.9547 | >.05 |
| NF200 | 50.0% | 53.3% | 2.7426 | >.05 |
| VIP | 31.3% | 37.6% | 11.3170 | .0092a |
| NPY | 8.0% | 5.3% | 7.7754 | >.05 |
Comparison of overall frequency of 12 immunohistochemical markers between ascending (n = 6) and descending colon (n = 6) considered for each marker separately. From the cell counts, chi-square values were calculated. P values are shown after Bonferroni correction for multiple tests, revealing that 3 markers showed significant differences in abundance between upper and lower colon.
5-HT, 5-hydroxytryptamine; Calb, calbindin; Calret, calretinin; CGRP, calcitonin gene-related peptide; ChAT, choline acetyltransferase; ENK, leu enkephalin; NF200, neurofilament 200 kD; NOS, neuronal nitric oxide synthase; NPY, neuropeptide Y; SOM, somatostatin; SP, substance P; VIP, vasoactive intestinal polypeptide.
Significant (P < .05).