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. 2023 Apr 27;228(5):564–575. doi: 10.1093/infdis/jiad116

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© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 7. — Avidity profile of antibodies from individuals of the “breakthrough infection” group against Omicron BA.1 antigens, with immunoglobulin (Ig) G, IgM, and IgA avidity, expressed as avidity index (AI), against recombinant spike and receptor-binding domain (RBD) antigens of Omicron BA.1 (n = 24). BA.1 refers to the sequence of the first isolate of the Omicron lineage. A parametric paired t test was performed to compare prebreakthrough (Pre) and postbreakthrough (Post) infection responses. ***P < .002; ***P < .001. Each symbol represents a single participant; bars, geometric means; and error bars, geometric standard deviations. Samples with AI <35, indicated by horizontal dotted lines, are considered to have low avidity.