Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 30;14:5283. doi: 10.1038/s41467-023-41025-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a 5-Hz-filtered EEG from an example hippocampal electrode from subject 12 for selected trials. Unlike the placebo condition, the 5-Hz-filtered oscillations in the scopolamine condition do not show phase alignment across trials. b Top: Inter-trial phase coherence (ITPC, or phase reset) during encoding for the same example electrode for the placebo and scopolamine conditions (0 ms denotes time of encoding cue). The increase in 5-Hz theta phase reset seen during the placebo session is not present during the scopolamine session. Magenta dashed lines indicate peak in ITPC between 0–300 ms for the placebo condition. Bottom: circular histograms showing phase distributions at the peak in ITPC following encoding cue for placebo (blue) and scopolamine (red). c Left: group-level mean phase reset across all hippocampal formation electrodes for the placebo and scopolamine conditions. Right: group-level mean change in phase reset between placebo and scopolamine. Black outline indicates significant clusters of change in phase reset (n = 69, p < 0.05, cluster-based permutation test, multiple-comparison corrected). Source data are provided as a source data file.