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. 1998 Apr;36(4):1074–1080. doi: 10.1128/jcm.36.4.1074-1080.1998

TABLE 1.

Comparison of M-capture ELISA results with other Lyme test results of other assays for LD for patient samples from patients with primary and secondary LDa

Type of LD and patient Culture for B. burgdorferi M-capture ELISA result with the following:
Result of IFA for IgM Result of EIA (recombinanti dot blot) for IgM Result of immunoblotting for IgM Result of polyvalent EIA
Sonicate + flagellin (IC) Sonicate (IC-derived antibody) Sonicate (free antibody)
Secondary
 MC-2 POS POS POS POS POS POS NEG POS
 MC-10 POS POS POS POS POS POS NEG POS
 MC-23 POS POS NEG NEG POS POS POS POS
 MC-28 POS POS POS ND POS POS POS POS
 MC-20 POS POS POS ND POS POS POS POS
 MC-3 POS POS POS ND POS NEG NEG NEG
 MC-14 POS POS POS ND POS POS POS POS
 MC-9 POS POS POS ND POS POS NEG POS
 MC-41 POS POS POS NEG POS EQUIV NEG POS
Primary
 MC-11 POS EQUIV EQUIV NEG POS NEG NEG NEG
 MC-35 POS POS POS POS NEG EQUIV POS NEG
 MC-48 POS POS POS POS POS NEG NEG NEG
 MC-55 POS POS POS POS POS EQUIV POS NEG
 MC-4 POS POS POS ND NEG NEG NEG NEG
 MC-17 POS POS NEG ND POS NEG NEG POS
 MC-36 POS POS POS ND NEG POS POS POS
 MC-72 POS POS POS ND EQUIV NEG POS POS
 MC-25 POS POS EQUIV POS POS NEG NEG NEG
 MC-24 POS NEG NEG NEG POS NEG NEG NEG
 MC-8 POS NEG NEG ND NEG NEG NEG NEG
a

Although results are presented for the M-capture ELISA done in three ways, the direct comparison to other tests for LD should be done with the serum sample containing IC-derived antibody and assayed with the biotinylated whole-cell sonicate (Bb-bio) plus the biotinylated flagellin synthetic epitope-BSA carrier (Fla-bio) as the antigen source. The other Lyme tests for LD are described in Materials and Methods. POS, positive; NEG, negative; EQUIV, equivocal; ND, not determined.