Table 2.
Characteristics of the GWAS summary data for serum micronutrients.
| Exposure | Outcome | |||||
|---|---|---|---|---|---|---|
| Trait | PMID | nSNP1 | nSNP2 |
P
(mr_presso) |
P
(pleiotropy) |
P
(heterogeneity) |
| Serum zinc | 26025379 | 21 | 20 | 0.21 | 0.44 | 0.98 |
| Serum copper | 26025379 | 25 | 25 | 0.55 | 0.33 | 0.54 |
| Serum iron | 33740060 | 3 | 3 | NA | 0.57 | 0.42 |
| Serum magnesium | 33740060 | 6 | 5 | 0.57 | 0.82 | 0.53 |
| Serum calcium | 33740060 | 7 | 7 | 0.25 | 0.78 | 0.14 |
| Serum selenium | 33740060 | 7 | 5 | 0.47 | 0.26 | 0.41 |
| Serum phosphate | 33740060 | 5 | 5 | 0.35 | 0.88 | 0.33 |
| Serum vitamin B12 | 33740060 | 9 | 9 | 0.06 | 0.80 | 0.03 |
nSNP1, the total SNPs after the screen using the p-value, physical distance (kb > 10,000), and linkage disequilibrium (R2 < 0.001); nSNP2, the total SNPs after the removal of incompatible, palindromic, and outlier SNPs; P (mr_presso): The P for the testing of outlier SNPs.