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. 2023 Aug 16;10:1211321. doi: 10.3389/fnut.2023.1211321

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Copyright © 2023 Pickering, Noah, Pereira, Goubayon, Leray, Touron, Macian, Bernard, Dualé, Roux and Chassain.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Whole-brain analysis of the BOLD responses of the Mg-Teadiola (D0 > D28) < Placebo (D0 > D28) contrast during pain stimulation Statistical t maps are overlaid on MNI slices using a voxel-wise threshold of p < 0.05 and an extent threshold of five voxels. They are covering frontal and prefrontal area (A), insula (B), and ventral striatum (C). Black arrow points each region of interest at L and R. Regions are automatically labeled using the Anatomy Toolbox atlas of SPM and are presented in the table below. x, y, and z are MNI coordinates in the L-R, anterior–posterior, and inferior–superior dimensions, respectively. All peaks are significant at a voxel-wise threshold of p < 0.05 (extend threshold = 5 voxels). L, left; R, right; MNI, Montreal Neurological Institute; SPM, Statistical Parametric Mapping.