Pattern of daily diary entries for the outcome of time to sustained (2 days) targeted symptom resolution for (A) high-risk and (B) standard-risk groups. Each row represents a participant. Meeting the outcome of all targeted symptoms resolved is given by a black dot. Green, orange, and purple boxes indicate days on which participants recorded at least 1 of 13 targeted symptoms being present (self-reported severity of mild, moderate, or severe) in their symptom diary. The color of the box reflects the worst symptom severity reported of all symptoms recorded as being present (green box if the worst severity reported was mild, orange box if the worst severity was moderate, and purple box if the worst severity was severe). An x indicates days when no data were recorded. Participants are grouped by outcome, from the top of the figure down: participants who never met the outcome, participants who met the outcome and did not report recurrent symptoms (ie, stayed resolved), and participants who met the outcome but subsequently reported recurrence of at least 1 targeted symptom.