TABLE 2.

Comparison of methods to identify isotopically labeled genomes ^a

Incorporator identification method	False positives	Specificity	Sensitivity	Balanced accuracy
qSIP model	7	0.993	0.857	0.925
ΔBD method	12	0.984	0.857	0.921
HR-SIP	9	0.991	0.571	0.781
MW-HR-SIP	4	0.996	0.857	0.927

^a Evaluations were based on absolute genome abundances obtained by normalizing coverage to internal sequin standards using the sequin approach. Specificity and sensitivity were averaged across the seven treatment conditions.