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. 2023 Aug 17;14:1242955. doi: 10.3389/fphar.2023.1242955

TABLE 1.

Natural products regulate glycolysis in NAFLD.

Name Origin Regulatory mechanism Dose Cell line/Experiment References
Gallic acid Cornus officinalis Increased levels of pyruvate and lactic acid 50 and 100 mg/kg HFD fed mice Chao et al. (2014)
Antrodan A. cinnamomea Inhibition of glucose and insulin levels via AMPK/Sirt1/SREBP-1c/PPARγ pathway 20 and 40 mg/kg HFD fed mice Chyau et al. (2020)
Vine tea Ampelopsis grossedentata Inhibition of F1,6P, G6P,6PG, F6P, pyruvate 500 and 2000 mg/L HFD fed rats Wan et al. (2017)
Extract of Caralluma fimbriata Caralluma fimbriata Increased levels of HK, PK, PFK 200 mg/kg HFD fed rats Gujjala et al. (2017)
Saskatoon berry Amelanchier alnifolia Nutt Increased levels of HK1 8 mg/kg HFD fed rats (du Preez et al., 2020)