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. 2023 Aug 17;14:1242955. doi: 10.3389/fphar.2023.1242955

TABLE 2.

Natural products regulate glycolysis in liver fibrosis.

Name Origin Regulatory mechanism Dose Cell line/Experiment References
Costunolide Radix Aucklandiae Inhibition of HK2 10, 20 and 30 μM Primary HSCs were isolated from rats Ban et al. (2019)
Deoxyelephantopin Elephantopus scaber L Inhibition of HK, PFK2, GLUT4 levels via hedgehog pathway 2.5, 5 and 10 μM Primary rat HSCs (HSC-T6) Gao et al. (2019)
Curcumin Curcuma longa L Inhibition of HK, PFK2, GLUT4 levels via AMPK pathway 20 μM Primary rat HSCs Lian et al. (2016)