TABLE 1.
Some ongoing clinical trials utilizing various gene panels/tests.
Gene panel/test | Number of genes | Utility | Ongoing (recruiting) clinical trials |
---|---|---|---|
PAM-50 (Pro-Signa) Wallden et al. (2015) | 50 | Prediction and risk assessment | 19- including NCT04344496, NCT03749421, NCT04759248, NCT03769415, NCT02889874, NCT01560663, NCT04578106, NCT03904173, NCT02448420, NCT04610528, NCT04759248 |
MammaPrint® Wittner et al. (2008) | 70 | Prediction and prognosis | 4- NCT05474391, NCT03053193, NCT03900637, NCT04129216 |
EndoPredict® Filipits et al. (2011) | 12 | Prognosis | 4- NCT04246606, NCT03503799, NCT03969121, NCT01805271 |
BluePrint® Mittempergher et al. (2020) | 80 | Diagnosis | 4- NCT03053193, NCT04129216, NCT05252416, NCT03900637 |
Oncotype DX® Paik et al. (2004) | 21 | Prediction | 11- NCT04852887, NCT03495011, NCT02476786, NCT01560663, NCT03212170, NCT03961880, NCT03703492, NCT02095184, NCT04797299, NCT02993159, NCT03220893 |
Invitae https://www.invitae.com/en/providers/test-catalog/test-01102 | 8 different kits with up to 84 genes | Prediction, risk assessment | 2- NCT04354675, NCT04985266 |