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. 2023 Aug 17;14:1219209. doi: 10.3389/fimmu.2023.1219209

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Copyright © 2023 Feng, Deng, Huang, Liu, Ruan, Wang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The cell infiltration characteristics in tumor microenvironment (TME) of four cuproptosis clusters. (A) The comparison of the abundance of immune cells infiltration in four cuproptosis clusters by single sample gene set enrichment analysis (ssGSEA) (*p< 0.05, **p< 0.01, ***p< 0.001, ****p< 0.0001; ns, no significance). (B–D) The stromal score (B), immune score (C), and tumor purity (D) of four cuproptosis clusters. (E–H) The differences in the expression levels of PD-1 (E), PD-L1 (F), CTLA-4 (G) and LAG-3 (H) among four cuproptosis clusters.