Table 1.
Basic and clinical data in the general population and subgroups according to VO and BMI categories
| Total study population (N = 520) |
Low BMI (N = 362) |
High BMI (N = 158) |
P
value |
Non-VO (N = 183) |
VO (N = 337) |
P
value |
|
|---|---|---|---|---|---|---|---|
| Age ≥ 65 years | 256 (49.23) | 184 (50.83) | 72 (45.57) | 0.270 | 72 (39.34) | 184 (54.60) | 0.001* |
| Gender (male) | 213 (40.96) | 150 (41.44) | 63 (39.87) | 0.739 | 88 (48.09) | 125 (37.09) | 0.015* |
| Smoking | 80 (15.38) | 59 (16.30) | 21 (13.29) | 0.382 | 22 (12.02) | 58 (17.21) | 0.117 |
| Hypertension | 164 (31.54) | 101 (27.90) | 63 (39.87) | 0.007* | 27 (14.75) | 137 (40.65) | 0.000* |
| Diabetes | 65 (12.50) | 39 (10.77) | 26 (16.46) | 0.072 | 9 (4.92) | 56 (16.62) | 0.000* |
| COPD | 44 (8.46) | 36 (9.94) | 8 (5.06) | 0.066 | 19 (10.38) | 25 (7.42) | 0.246 |
| Coronary heart disease | 56 (10.77) | 37 (10.22) | 19 (12.03) | 0.542 | 10 (5.46) | 46 (13.65) | 0.004* |
| Cerebral infarction | 73 (14.04) | 51 (14.09) | 22 (13.92) | 0.960 | 13 (7.10) | 60 (17.80) | 0.001* |
| Fatty liver | 27 (5.19) | 10 (2.76) | 17 (10.76) | 0.000* | 1 (0.55) | 26 (7.72) | 0.000* |
| Anemia | 158 (30.38) | 119 (32.87) | 39 (24.68) | 0.062 | 59 (32.24) | 99 (29.38) | 0.498 |
| Low albumin | 173 (33.27) | 131 (36.19) | 42 (26.58) | 0.033* | 67 (36.61) | 106 (31.45) | 0.233 |
| Fasting blood glucose | 5.31 (4.88, 5.81) | 5.31 (4.80, 5.68) | 5.38 (5.06,6.13) | 0.000* | 5.20 (4.71, 5.46) | 5.31 (4.98, 6.04) | 0.000* |
| WBC (×109 /L) | 6.20 (5.10, 7.30) | 6.00 (5.10, 7.10) | 6.40 (5.30, 7.50) | 0.110 | 5.90 (4.90, 7.05) | 6.30 (5.20, 7.50) | 0.077 |
| Neutrophil (×109 /L) | 3.78 (2.91, 4.76) | 3.71 (2.92, 4.67) | 3.86 (2.89, 4.92) | 0.397 | 3.66 (2.94, 4.55) | 3.85 (2.90, 4.85) | 0.472 |
| LMR | 4.58 (3.48, 5.94) | 4.41 (3.23, 5.90) | 4.80 (3.85, 6.05) | 0.009* | 4.36 (3.30, 5.92) | 4.63 (3.53, 5.94) | 0.349 |
| Operation time ≥ 4 h | 174 (33.46) | 108 (29.83) | 66 (41.77) | 0.008* | 55 (30.05) | 119 (35.31) | 0.225 |
| Surgical approach | 0.687 | 0.146 | |||||
| Laparoscopy | 463 (89.04) | 321 (88.67) | 142 (89.87) | 158 (86.34) | 305 (90.50) | ||
| Open | 57 (10.96) | 41 (11.33) | 16 (10.13) | 25 (13.66) | 32 (9.50) | ||
| Perioperative blood infusion | 76 (14.62) | 57 (15.75) | 19 (12.03) | 0.269 | 29 (15.85) | 47 (13.95) | 0.558 |
| Ostomy | 165 (31.73) | 109 (30.11) | 56 (35.44) | 0.230 | 55 (30.05) | 110 (32.64) | 0.545 |
| Pathology | 0.485 | 0.205 | |||||
| Adenocarcinoma | 443 (85.19) | 311 (85.91) | 132 (83.54) | 151 (82.51) | 292 (86.65) | ||
| Nonadenocarcinoma | 77 (14.81) | 51 (14.01) | 26 (16.46) | 32 (17.49) | 45 (13.35) | ||
| Tumor location | 0.811 | 0.416 | |||||
| Rectum | 246 (47.31) | 170 (46.96) | 76 (48.10) | 91 (49.73) | 155 (45.99) | ||
| Colon | 274 (52.69) | 192 (53.04) | 82 (51.90) | 92 (50.27) | 182 (54.01) | ||
| Histologic type | 0.006* | 0.643 | |||||
| Low | 119 (22.88) | 95 (26.24) | 24 (15.19) | 44 (24.04) | 75 (22.26) | ||
| Medium-high | 401 (77.12) | 267 (73.76) | 134 (84.81) | 139 (75.96) | 262 (77.74) | ||
| Tumor diameter (Max)(cm) | 4.50 (3.50, 6.00) | 4.50 (3.65, 6.00) | 4.50 (3.50, 5.90) | 0.305 | 4.80 (4.00, 6.00) | 4.50 (3.50, 5.60) | 0.054 |
| Pathological stage | 0.398 | 0.005* | |||||
| < II B stage | 216 (41.54) | 146 (40.33) | 70 (44.30) | 61 (33.33) | 155 (45.99) | ||
| ≥ II B stage | 304 (58.46) | 216 (59.67) | 88 (55.70) | 122 (66.67) | 182 (54.01) |
Anemia, hemoglobin concentration < 120 g/L for men and < 110 g/L for women
Low albumin, albumin < 40 g/L; BMI, body mass index; VO, visceral obesity, visceral fat area ≥ 100 cm2; High BMI, BMI ≥ 25 kg/m2; SFA, subcutaneous fat area; COPD, chronic obstructive pulmonary disease; LMR, lymphocyte to monocyte ratio
Data are presented as numbers (%) or medians (interquartile range)
*Compared with the low BMI group, P < 0.05
*Compared with the non-VO group, P < 0.05