Table 2.
Amount of clonotypes in baseline, end-of-trial and specific T cell cultures.
| Patient | Chain | N, clonotypes, baseline |
N, clonotypes, end of trial | N, clonotypes in specific fraction cells | N, clonotypes in specific fraction > 1% frequency | Fraction of specific clonotypes in baseline sample | Fraction of specific clonotypes in end-of-trial sample | Fraction of specific clonotypes in the specific T cell sample |
|---|---|---|---|---|---|---|---|---|
| 1 | α | 3601 | 5113 | 110 | 23 | 0% | 0,022% | 89,011% |
| β | 11837 | 20857 | 198 | 22 | 0% | 0,039% | 86,089% | |
| 2 | α | 4868 | 8935 | 25 | 5 | 0% | 0% | 99,028% |
| β | 24124 | 35587 | 27 | 5 | 0% | 0,001% | 99,492% | |
| 7 | α | 14159 | 3420 | 3 | 2 | 0% | 0,018% | 99,877% |
| β | 52996 | 10896 | 206 | 1 | 0% | 0% | 99,477% | |
| 9 | α | 4831 | 962 | 279 | 19 | 0% | 0% | 82,825% |
| β | 11941 | 3113 | 958 | 13 | 0,016% | 0,046% | 69,027% |