REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological samples
Human placental tissue	University of California, San Francisco (UCSF)	N/A
Chemicals, peptides, and recombinant proteins
Ham’s F-12K (Kaighn’s) Medium	Gibco	Cat#21127022
Dulbecco’s modified Eagle’s medium	Gibco	Cat#21068028
Fetal bovine serum	Sigma-Aldrich	Cat#F0926
Penicillin-streptomycin	Gibco	Cat#15140122
Gentamicin	Gibco	Cat#15750060
DPBS	Gibco	Cat#14190250
DME/H-21	Gibco	Cat#11995065
Glutamine plus	Atlanta Biologicals	Cat#B90210
Nutridoma	Roche	Cat#11011375001
Sodium pyruvate	Gibco	Cat#11360070
HEPES buffer	Gibco	Cat#15630080
SYBR™ Green qPCR Master Mix	Applied Biosystems	Cat#43-676-59
10% Neutral Buffered Formalin	RPI	Cat#F10800–500.0
Ethanol 200PRF	Decon Labs	Cat#V1001
Critical commercial assays
Human Luminex Premixed Multi-Analyte Kit	Bio-Techne	Cat#LXSAHM
RNeasy Micro Kit	Qiagen	Cat#74004
qScript cDNA Synthesis Kit	Quantabio	Cat#95047-100
RNAscope® 2.5 HD Reagent Kit - RED	ACD	Cat#322350
Experimental models: Cell lines
BeWo choriocarcinoma cells	ATCC	CCL-98
JEG-3 choriocarcinoma cells	ATCC	HTB-36
A549 lung carcinoma cells	ATCC	CCL-185
293T cells	ATCC	CRL-3216
Oligonucleotides
BNT162b2 vaccine	Pfizer-BioNTech	N/A
mRNA-1273 vaccine	Moderna	N/A
RNAscope Probe -V-nCoV2019-S	ACD	Cat# 848561
RNAscope Positive Control Probe -Hs-PPIB	ACD	Cat# 313901
RNAscope Negative Control Probe - DapB	ACD	Cat# 310043
Forward primer for COVID mRNA vaccines 5′-AACGCCACCAACGTGGTCATC -3′	Golan et al.16	N/A
Reverse primer for COVID mRNA vaccines 5′-GTTGTTGGCGCTGCTGTACAC -3′	Golan et al.16	N/A
Software and algorithms
GraphPad Prism 9	GraphPad	https://www.graphpad.com/
R studio 2022.12.0 + 353 (R 4.2.2)	RStudio, Inc.	https://www.rstudio.com/
LAS Science Microscope Software	Leica	https://www.leica-microsystems.com