Table 5.
Multiple linear regression analysis of determinants of CT attenuation and thymic size. Independent determinants of CT attenuation values are presented in subjects with any detectable thymic tissue (Score ≥ 1, n = 433) and thymic size in all subjects (n = 1078)
| β | P | Adjusted R2 | ||
|---|---|---|---|---|
| CT attenuationa (HU) | Abdominal obesity | -0.206 | < 0.001 | 0.16 |
| HDL cholesterol | 0.195 | 0.003 | ||
| Naïve CD8 + T cells, % of all CD8+ | 0.165 | 0.002 | ||
| Thymic sizeb (AP diameter, mm) | Abdominal obesity | 0.150 | 0.006 | 0.28 |
| HDL cholesterol | -0.242 | < 0.001 | ||
| BMI | 0.301 | < 0.001 |
HU Hounsfield units, AP Anteroposterior. β indicates standardized coefficient. Variables included but not retaining statistical significance in the models:
aage, sex, BMI, triglycerides, CRP
bage, triglycerides and CRP