TABLE 2.
Frequency of intravitam diagnosis of rabies in nine patients in France (1986–1997)
| Specimen type | Method(s)a | Frequency of rabies diagnosisb
|
Sensitivityd | |||||
|---|---|---|---|---|---|---|---|---|
| 0–4 daysc | 5–8 days | 9–12 days | 13–16 days | >16 days | Unknown date | |||
| Serum | Serology (ELISA, RFFIT) | 0/4 | 1/2 | 0/2 | 1/1 | 0/3 | 0.17 (n = 12) | |
| CSF | Serology (ELISA, RFFIT) | 0/4 | 0/1 | 0/3 | 1/1 | 0/3 | 0.08 (n = 12) | |
| RT-PCR | 0/5 | 1/3 | 0/2 | 0/1 | 0/2 | 1/9 | 0.09 (n = 22) | |
| Saliva | RREID | 0/1 | 0/5 | 0/4 | 0/4 | 1/4 | 0/1 | 0.05 (n = 19) |
| RT-PCR | 1/5 | 3/8 | 1/5 | 0/4 | 3/6 | 3/9 | 0.30 (n = 37) | |
| Skin biopsy | IF | 3/3 | 2/2 | 0/1 | 1/1 | 0.86 (n = 7) | ||
a
RFFIT, rapid fluorescent focus inhibition test; RREID, rapid rabies enzyme immunodiagnosis for rabies antigen detection.
b
The number of patients diagnosed with rabies relative to the total number is given.
c
Days after onset of symptoms.
d
n = number of samples.