TABLE 2.

Antihypertensive effects of beta-blockers, RAS blockers, calcium-channel blockers, thiazides and renal denervation.

	Beta-blockers	RAS blockers	Calcium-channel blockers	Thiazides	Renal denervation
BP decrease, sustainability	years, decades	years, decades	years, decades	years, decades	months
BP paradox responders	yes	?	no	no	yes
BP variability	?	?	↓↓↓	↓↓	↓
BP decrease age dependent	yes	yes	no	no	yes
Heart rate	↓↓	no	no	no	↓
Plasma renin activity	↓↓	↑↑↑	?↑	↑↑	↓↓
Sympathetic activity	↓↓	↓	no	↑	↓↓
Morbidity and mortality	inconsistent evidence	↓↓	↓↓	↓↓↓	no evidence