Fig 7.

Changes in FLC susceptibility (MIC₅₀ and MIC₉₀, (A) and tolerance (SMG, B) of other yeast species using combinations of potentiators (100 µM) and fluconazole (FLC) (from 0 to 256 µg/mL). Values are shown relative to DMSO controls. R, FLC-resistant isolates (MIC₅₀ ≥16 µg/mL for Candida glabrata and MIC₅₀ ≥4 µg/mL for all other species); T, FLC-tolerant isolates (SMG ≥0.5). Heatmaps show average values from three to four biological replicates. (C) Lines indicate phylogenetic relationships between different species, adapted with permission from Ref. (49).