Table 2.
Health-related Quality of Life Profile by the EORTC QLQ-C30 According to Risk Categories of the IPSS and IPSS-R in Newly Diagnosed Patients With MDS
| IPSS-risk Group | IPSS-R-risk Groupa | |||
|---|---|---|---|---|
| Lower N = 506 |
Higher N = 421 |
Lower N = 381 |
Higher N = 521 |
|
| Scale | M (SD) | M (SD) | M (SD) | M (SD) |
| A. Functional scales and global health status/QoL | ||||
| Physical functioning | 75.1 (21.8) | 70.2 (23.4) | 77.2 (21.3) | 69.9 (23.2) |
| Role functioning | 76.8 (28.7) | 67.9 (30.4) | 78.4 (28.8) | 69.3 (29.9) |
| Emotional functioning | 75.3 (20.9) | 71.1 (24.1) | 75.4 (20.8) | 71.6 (23.8) |
| Cognitive functioning | 82.2 (20.7) | 81.6 (22.9) | 82.6 (20.9) | 81.3 (22.5) |
| Social functioning | 85.0 (23.0) | 74.0 (29.4) | 87.1 (21.7) | 75.1 (28.8) |
| Global health status/QoL | 61.9 (22.5) | 54.6 (23.1) | 63.2 (22.9) | 55.3 (22.6) |
| B. Symptom scales/items | ||||
| Fatigue | 34.1 (25.8) | 41.7 (27.0) | 32.3 (25.7) | 41.4 (26.8) |
| Nausea/vomiting | 4.2 (9.8) | 7.2 (15.6) | 4.0 (10.1) | 6.6 (14.5) |
| Pain | 16.7 (23.1) | 20.1 (25.3) | 15.8 (22.0) | 19.8 (25.4) |
| Dyspnea | 26.0 (29.1) | 29.7 (29.7) | 23.8 (28.2) | 29.8 (29.7) |
| Insomnia | 25.0 (28.3) | 25.9 (29.6) | 25.4 (28.1) | 25.7 (29.7) |
| Appetite loss | 12.7 (23.8) | 20.7 (29.2) | 11.5 (23.1) | 19.6 (28.7) |
| Constipation | 15.2 (24.3) | 18.5 (28.9) | 14.5 (23.7) | 18.8 (28.6) |
| Diarrhea | 6.9 (16.9) | 6.7 (17.5) | 7.0 (17.5) | 6.7 (17.0) |
| Financial problems | 9.8 (22.9) | 14.4 (26.2) | 9.0 (22.8) | 13.7 (25.4) |
aFor 25 patients, the IPSS-R classification was not available in the dataset.
Questionnaire-Core30; IPSS = International Prognostic Scoring System; IPSS-R = International Prognostic Scoring System-Revised; QoL = quality of life; M = mean.