Fig 2. Changes in cellular metabolism induced by decalin-containing tetramic acids.
Percentage changes in OCR and ECAR (relative to their respective baseline values) induced by test compounds were calculated from S14 Fig. Each data point represents the mean ± standard deviation value at 6 min after sample treatment (n = 3). Note that decreasing OCR and increasing ECAR is a typical phenotype characteristic to mitochondrial respiration inhibitors [20].
