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. 2023 Sep 1;133(17):e167693. doi: 10.1172/JCI167693

Figure 3. cGMP induces cardioprotection.

Figure 3

(A) Percentage recovery of LVDP and (B) infarct size after administration of buffer (n = 8), cGMP (0.1 mM, n = 7) in buffer, or cGMP following administration of MK571 (n = 7). (C) Recovery of LVDP after administration of cGMP (0.1 mM, n = 7) in buffer or following administration of recombinant PDE5 (n = 6). Data are presented as mean ± SD. The data points in the Buffer group are the same as those in the Figure 1 Buffer group. **P < 0.01 and ***P < 0.001 denote significant differences between groups or compared with vehicle in A using 2-way ANOVA followed by followed by Tukey’s multiple comparison test in A and C and 1-way ANOVA followed by Tukey’s multiple comparison test in B.