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. 2023 Aug 17;13:1195814. doi: 10.3389/fonc.2023.1195814

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Copyright © 2023 Akrout, Achour, Tops, Gallon, Meddeb, Achoura, Ben Rekaya, Hamdeni, Rammeh, Chkili, Mansouri, Belguith and Mrad

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Preoperative cranial MRI of the proband (from left to right: axial T1-weighted with gadolinium injection, axial T2 FLAIR-weighted, axial apparent diffusion coefficient). There is a solid intra-axial mass within the right frontal lobe with marked ring-like enhancement and an internal necrotic area. The enhancing component of the lesion shows diffusion restriction. (B) Timeline showing the clinical history of the patient. (C) Family pedigree. The black arrow indicates the proband case. The age of the first tumor is given below the proband and the two affected brothers.