Fig. 2.

Frequencies and distributions of Lys⁺ revertants in strains with altered core NHEJ proteins. a) Mean frequencies of Lys⁺ colonies; error bars are 95% confidence intervals for the mean. b) Distributions of the 5 major NHEJ types among revertants. Overall distributions were compared to WT using a global 2 × 5 contingency chi-square test (P-values are above each spectrum) and if P < 0.05, then individual mutation types were compared using the Bonferroni correction to determine significance (P < 0.05/5); asterisks indicate a significant proportional class increase/decrease.