Table 3.

The efficacy of AZM, BDQ, and WX-081 against Mycobacterium Abscess infection in zebrafish in vivo.

Groups	concentration (μg/mL)	Whole-body fluorescence intensity (pixel, mean ± SE)	Head fluorescence intensity (pixel, mean ± SE)
Control group (n = 10)	–	361707 ± 7139**	55473 ± 2670**
Model group (n = 10)	–	671089 ± 22305	132412 ± 9989
AZM (n = 10)	62.5	433684 ± 11910**a3	78397 ± 4815**
BDQ (n = 10)	15.6	438648 ± 8280**a1	79664 ± 5809**
WX-081 (n = 10)	1.95	535952 ± 23902**a1	101579 ± 6065a3
	3.91	520519 ± 18208**a1	101495 ± 10160a2
	7.81	492988 ± 17182**a1	93190 ± 5468a2
	15.6	462296 ± 14360**a1	89877 ± 10333*
	31.2	419947 ± 13302**a2	76778 ± 4906**
	62.5	375347 ± 11359**	70976 ± 5726**

Compared with the model control group, *p < 0.05, **p < 0.01.

Compared with 62.5 μg/mL WX-081, ^a1p < 0.001, ^a2p < 0.05, ^a3p < 0.01.