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. 2022 Oct 21;37(9):828–834. doi: 10.1038/s41371-022-00766-x

Table 5.

Estimated annual requirement of drugs per patient and annual cost of medication (in USD) for hypertension treatment with the use of selected protocols.

Protocol Scenario Treatment stage-wise control assumption Approximate annual drug requirement per patient Annual cost of medication per patient in USD
Amlodipine 5 mg Telmisartan 40 mg Chlorthalidone 12.5 mg Total pill requirement Private sector Private low-cost generic Govt. program
Protocol 1: AATTC 1 30:30:20:10:10 621 219 37 876 47.61 8.09 3.00
2 40:25:15:10:10 584 201 37 821 44.46 7.57 2.81
3 50:20:15:10:5 548 164 18 730 38.10 6.46 2.32
4 60:15:13:7:5 511 135 18 664 33.88 5.78 2.05
Protocol 2: ATTAC 1 30:30:20:10:10 438 402 37 876 58.44 9.57 3.89
2 40:25:15:10:10 438 347 37 821 53.12 8.76 3.52
3 50:20:15:10:5 420 292 18 730 45.68 7.50 2.94
4 60:15:13:7:5 409 237 18 664 39.95 6.61 2.55
Scenario Treatment stage-wise control assumption Amlodipine 5mg + Telmisartan 40mg SPC Chlorthalidone 12.5mg Total pill requirement Private sector Private low-cost generic Govt. program
WHO-HEARTS SPC protocol 3 1 30:30:30:10 456 37 493 68.83 9.89 3.98
2 40:30:20:10 420 37 456 63.55 9.15 3.69
3 50:20:25:5 383 18 402 56.84 8.09 3.23
4 60:15:20:5 347 18 365 51.57 7.35 2.94

Exchange rate USD: INR used is 1:74.