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. 2023 Aug 28;26(9):1584–1594. doi: 10.1038/s41593-023-01413-5

Extended Data Fig. 10. Pre-stimulus pupil size does not influence trial outcome.

Extended Data Fig. 10

(a) Pupil size was measured for 3 sessions (sessions 7, 8 and 9, corresponding to Supplementary Fig. 2), see Methods. (b) Trial- and session-averaged pupil size dynamics for hit and miss trials, where shaded areas indicate the 95% confidence interval of the mean (across sessions and trials). The time-averaged pre-stimulus pupil size was not significantly different between hit and miss trials (two-sided t-test). (c) Population variance was very weakly correlated to pupil size across all sessions (both averaged across 500 ms pre-stimulus per trial) (two-sided Pearon correlation r = 0.12, p = 0.02). (d–f) Trial-averaged pupil size dynamics per session, where shaded areas indicate the 95% confidence interval of the mean (across trials). Pre-stimulus differences between hit and miss were not significant for any of the sessions (two-sided t-tests), although session 7 (panel d) almost reached the significance threshold (p = 0.053). (g–i) Population variance vs pupil size per session. Two-sided Pearson’ correlation was significant for only one of the sessions (session 7).