Fig. 8. Associations between microbial taxonomic groups and metabolites from two chemical subclasses are associated with specific dominant coral reef benthic producers.

Binary biclusters indicate the presence/absence of microbe-metabolite co-occurrence (mmvec) for (a) long chain fatty acids and (b) glycerophosphocholines (see Fig. 1c). A filled tile indicates that the microbe and metabolite co-occurred. The color of the tile indicates the primary producer type in which the microbe and metabolite co-occurred. Metabolites (rows) are arranged by structural relatedness (Qemistree). Microbes (columns) are arranged by phylogenetic relatedness (16 S FastTree). Metabolites that matched known spectra are annotated with their putative molecular names. Metabolites that were significantly associated with primary producer type are indicated with “*”. Several associations between specific metabolites and microbial families are highlighted. Dot plots show the log relative abundance of microbial families against the log relative abundance of ion features across all samples. The names of the ion features were retrieved from spectral library matches of the feature-based molecular networking workflow, and the compounds present in the samples could be their isomers.