Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 31;14:5291. doi: 10.1038/s41467-023-41117-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — a Partial least-squares-discriminant analysis (PLS-DA) of differential gene expression between HOCl-induced (dark gray) and untreated (control, light gray) group, or HOCl-induced groups treated with D11 (red), E07 (blue) or TD139 (purple), and HOCl untreated group. The number of upregulated (up arrow) or downregulated (down arrow) genes with false discovery rate (FDR) below 0.05 and absolute fold-change (FC) above 1.3 refers to each relevant comparative analysis. b Gene expression heatmap showing the 510 genes differentially expressed between the HOCl-induced and control groups, and their modulation by each anti-Gal-3 treatment. Each column represents the mean relative gene expression levels of n = 11 (control) or n = 12 (HOCl, D11, E07, TD139) mice per group. Each gene is represented by one horizontal line. Gene expression intensities are displayed as colors ranging from blue for the lowest expression level to red for the highest expression level as shown in the key. The relative FC and FDR values are reported in Supplementary Data 3.