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. 2023 Aug 30;10(2):e002382. doi: 10.1136/openhrt-2023-002382

Table 2.

Mendelian randomisation causal estimates and standard estimates for lipoprotein(a) with glycated haemoglobin and estimated glomerular filtration rate in UK Biobank participants at study baseline by ancestral population

Statistical method African (n=7529) East Asian (n=2156) European (n=326 028) South Asian (n=8048)
Β (SE) P value Β (SE) P value Β (SE) P value Β (SE) P value
Estimated glomerular filtration rate
 MR 0.019 (0.47) 0.31 0.064 (0.99) 0.15 0.0013 (0.0021) 0.53 0.0062 (0.020) 0.76
 Standard 0.025 (0.010) 0.014 0.010 (0.017) 0.58 0.0086 (0.0015) 1.7×10–8 0.027 (0.010) 0.039
Glycated haemoglobin
 MR 0.065 (0.13) 0.60 0.34 (0.23) 0.14 0.044 (0.0091) 1.4×10–6 0.12 (0.12) 0.31
 Standard 0.23 (0.70) 5.0×10–3 0.035 (0.087) 0.68 0.13 (0.0067) 5.4×10–87 0.048 (0.053) 0.36

MR, Mendelian randomisation.