Table V.

Adjusted hazard ratios of sleep disorders in patients with prurigo nodularis vs controls, stratified by age and sex

Subgroup	Prurigo nodularis vs controls
Outcome	Insomnia			Sleep apnea			Restless legs syndrome			Overall sleep disorder
	aHR	95% CI	P value	aHR	95% CI	P value	aHR	95% CI	P value	aHR	95% CI	P value
Total	1.77	1.48-2.12	<.005	1.51	0.93-2.44	.10	1.54	0.92-2.57	.10	1.72	1.46-2.02	<.005
Age, y
<30	1.56	0.88-2.76	.13	2.34	0.31-17.7	.41	1.53	0.18-12.6	.70	1.59	0.93-2.74	.09
30-39	2.09	1.12-3.91	.02	2.94	0.76-11.3	.12	3.48	0.14-85.5	.45	2.26	1.28-3.98	<.005
40-49	2.09	1.36-3.20	<.005	1.62	0.57-4.56	.36	2.70	0.44-16.5	.28	2.05	1.38-3.05	<.005
50-59	1.55	1.05-2.28	.03	1.36	0.58-3.19	.48	2.26	0.77-6.60	.14	1.66	1.18-2.34	<.005
60-69	2.08	1.36-3.17	<.005	1.05	0.31-3.56	.94	0.98	0.47-2.07	.97	1.76	1.23-2.53	<.005
70-79	1.20	0.76-1.89	.43	0.39	0.04-4.42	.45	1.88	0.56-6.31	.31	1.17	0.77-1.80	.46
≥80	2.67	1.34-5.41	.01	1.05	0.07-16.1	.97	0.65	0.08-5.09	.68	2.39	1.25-4.57	.01
Sex
Male	1.74	1.30-2.32	<.005	1.43	0.76-2.68	.27	1.36	0.55-3.37	.51	1.66	1.28-2.14	<.005
Female	1.79	1.42-2.26	<.005	1.37	0.64-2.92	.42	1.69	0.90-3.16	.10	1.76	1.42-2.17	<.005

Bold values denote statistical significance at the P < .05 level.

aHR, Adjusted hazard ratio.