Table 1.

Characteristics of the cohort of patient with iTTP

Characteristics	n	%
Total number of patients with iTTP	83∗
Sex
Female	61	73
Male	22	27
Ethnicity
Caucasian	83	100
Observation time, d
Median (minimum, 25th percentile, 75th percentile, maximum)	468 (1, 56, 680, 782)
Age at time of enrollment, y
Median (minimum, 25th percentile, 75th percentile, maximum)	49 (20, 39, 57, 86)
Age at time of diagnosis of first acute iTTP episode, years†
Median (minimum, 25th percentile, 75th percentile, maximum)	38 (12, 27, 49, 85)
Number of acute TTP episodes during study	22 in 16 patients
Patients enrolled during acute iTTP	8
Initial diagnosis during study	4
Relapse of iTTP	4
Relapses during follow-up after enrollment	14
Number of patients with iTTP in continued remission during study	67
Number of all acute episodes per patient before enrollment into the study‡
Median (minimum, 25th percentile, 75th percentile, maximum)	2 (0, 1, 3, 23)
Risk factors for iTTP
Smoking	17	20
Overweight (BMI, 27-29.9)§	12	16
Obesity (BMI >30)§	26	34
Arterial hypertension	28	31
Type 1 diabetes mellitus	1	1
Type 2 diabetes mellitus	11	13

BMI, body mass index.

^∗Ninety-one patients were screened (refer to supplemental Figure 1).

^†Known for 80 patients with iTTP.

^‡Known for 75 patients with iTTP.

^§Known for 76 patients with iTTP.