Table 1.
Evaluation of stability and organoleptic parameter studies of I. carnea herbal cream.
|
Test |
Days | Plain cream | FIHC 50 mg concentration | FIHC 100 mg concentration | FIHC 200 mg concentration | Accelerated stability condition |
|---|---|---|---|---|---|---|
| Color | 0 | White | Pale green | Pale green | Dark green | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | NCC | NCC | NCC | NCC | ||
| Physical appearance | 0 | Semi solid | Semi solid | Semi solid | Semi solid | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | NCC | NCC | NCC | NCC | ||
| Odor | 0 | No odor | Herbal fragrance | Herbal fragrance | Herbal fragrance | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | NCC | NCC | NCC | NCC | ||
| Homogeneity | 0 | Smooth | Smooth | Smooth | Smooth | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | NCC | NCC | NCC | NCC | ||
| Spreadability (g/cm/sec) | 0 | 18.3 ± 0.5 | 12.66 ± 0.5 | 12.33 ± 0.5 | 9.63 ± 0.5 | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | 18.6 ± 0.5 | 13.1 ± 0.5 | 12.66 ± 0.5 | 11.62 ± 0.5 | ||
| pH | 0 | 6.2 ± 0.1 | 6.1 ± 0.1 | 6.2 ± 0.1 | 6.3 ± 0.1 | 40 °C ± 2 °C/75% ± 5% RH |
| 90 | Within range | Within range | Within range | Within range |
NCC- Non characteristic changes, RH- Relative humidity.