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. 2023 May 19;21(9):933–946. doi: 10.1158/1541-7786.MCR-22-0820

Figure 2.

Figure 2. Deleting Ripk3 or Mlkl reduced CD-HFD induced inflammation in male mice. Transcript levels of hepatic IL6 (A), circulating IL6 (B), transcript levels of hepatic TNFα (C), and circulating TNFα (D) in male (left) and female (right) mice. E, Left: Images of H&E stained sections. Black dotted circles represent KC clusters. Scale bar: 50 μm. Right: Graphical representation of the number of KC clusters in each group. Males: NC (white), CD-LFD (light blue) or CD-HFD (dark blue). Females: NC (white), CD-LFD (light orange) or CD-HFD (dark orange).

Deleting Ripk3 or Mlkl reduced CD-HFD induced inflammation in male mice. Transcript levels of hepatic IL6 (A), circulating IL6 (B), transcript levels of hepatic TNFα (C), and circulating TNFα (D) in male (left) and female (right) mice. E, Left: Images of H&E stained sections. Black dotted circles represent KC clusters. Scale bar: 50 μm. Right: Graphical representation of the number of KC clusters in each group. Males: NC (white), CD-LFD (light blue) or CD-HFD (dark blue). Females: NC (white), CD-LFD (light orange) or CD-HFD (dark orange).