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. 2023 Aug 17;14:1195247. doi: 10.3389/fendo.2023.1195247

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Copyright © 2023 Xiao, Pietzner, Rohwer, Jung, Rothe, Weylandt and Elbelt

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of plasma 5-lipoxygenase (LOX), 12-LOX and 15-LOX metabolites derived from arachidonic acid (AA) (A), EPA (B), DHA (C), γ-linolenic acid (γ-LA) (D) and the LOX metabolites level derived from LA (E) and α-LA (F), as well as leukotrienes derived from AA (G). All results are shown as the mean ± SEM, p values are based on t-test or Mann-Whitney test; Significant changes are indicated as: *p < 0.05; **p < 0.01; HETE, hydroxyeicosatetraenoic acid; HEPE, hydroxyeicosapentaenoic acid; HDHA, hydroxydocosahexaenoic acid; HODE, hydroxyoctadecadienoic acid; HETrE, hydroxyeicosatrienoic acid; HOTrE, hydroxyoctadecatrienoic acid; LTB4, leukotriene B4.