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. 2023 Aug 17;14:1195247. doi: 10.3389/fendo.2023.1195247

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Copyright © 2023 Xiao, Pietzner, Rohwer, Jung, Rothe, Weylandt and Elbelt

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of plasma cytochrome P450 (CYP) epoxygenase metabolites level derived from AA (A), EPA (B), DHA (C), as well as CYP450 ω-hydroxylase metabolites level of AA (20-HETE), EPA (20-HEPE), and DHA (22-HDHA) (D). All results are shown as the mean ± SEM, P values are based on t-test or Mann-Whitney test; Significant changes are indicated as: *p < 0.05; **p < 0.01; EET: epoxyeicosatrienoic acid; DHET: dihydroxy-eicosatetraenoic acid; EEQ: epoxyeicosatetraenoic acid; DiHETE: dihydroxy-eicosatetraenoic acid; EDP: epoxydocosapentaenoic acid; DiHDAP: dihydroxy-docosapentaenoic acid; EpOME: epoxyoctadecamonoenoic acid; DiHOME: dihydroxy-octadecenoic acid.