Table 1. Change in anthropometry after each cycle of weight loss in the T2D group.
| Baseline, n=20 | 8 weeks, n=20 | 16 weeks, n=18 | 24 weeks, n=9 | 52 weeks, n=15 | Control, n=20 | |
|---|---|---|---|---|---|---|
| Weight (kg) | 71.8 ± 2.8 | 67.0 ± 2.7 P=0.0001 |
65.3 ± 2.9 P=0.0001 |
62.6 ± 4.2 P=0.0001 |
64.1 ± 2.8 P=0.0001 |
61.5 ± 2.5 P=0.496 |
| BMI (kg/m2) | 24.8 ± 0.4 | 23.2 ± 0.4 P=0.0001 |
22.4 ± 0.4 P=0.0001 |
21.3 ± 0.5 P=0.0001 |
22.4 ± 0.5 P=0.0001 |
21.5 ± 0.5 P=0.226 |
| Change in BMI (%) | - | −6.6-± 0.5 | −9.9-± 0.5 | −14.1 ± 1.0 | −9.9 ± 1.1 | – |
| Fat free mass (kg) | 49.0 ± 2.6 | 48.0 ± 2.6 P=0.004 |
47.5 ± 2.8 P=0.0001 |
46.6 ± 3.8 P=0.0001 |
47.1 ± 3.0 P=0.0001 |
46.4 ± 2.2 P=0.845 |
| Total body fat (%) | 32.1 ± 1.5 | 28.8 ± 1.6 P=0.0001 |
27.7 ± 1.5 P=0.0001 |
25.8 ± 2.3 P=0.0001 |
27.7 ± 1.8 P=0.0001 |
24.6 ± 1.5 P=0.214 |
| Female | 36.3 ± 0.9 | 33.2 ± 1.0 P=0.0001 |
31.4 ± 1.0 P=0.0001 |
29.5 ± 1.7 P=0.0001 |
32.0 ± 0.9 P=0.0001 |
27.5±1.7 P=0.037 |
| Male | 24.2 ± 1.2 | 20.6 ± 1.3 P=0.0001 |
20.3 ± 1.5 P=0.0001 |
– | 19.2 ± 1.8 P=0.006 |
19.2 ± 1.7 P=0.983 |
| Waist circumference (cm) | 90.0 ± 2.1 | 83.4 ± 1.9 P=0.001 |
80.9 ± 2.1 P=0.001 |
77.2 ± 2.7 P=0.001 |
79.7 ± 2.0 P=0.001 |
75.6 ± 1.8 P=0.140 |
| Female | 85.6 ± 2.0 | 79.7 ± 1.6 P=0.001 |
76.8 ± 1.7 P=0.001 |
73.6 ± 2.0 | 76.4 ± 1.4 P=0.001 |
71.1 ± 1.5 P=0.022 |
| Male | 98.1 ± 3.0 | 90.3 ± 3.2 P=0.001 |
89.0 ± 3.5 P=0.001 |
– | 86.8 ± 3.8 P=0.001 |
83.9 ± 2.1 P=0.534 |
| VAT (cm2) | 143.2 ± 17.7 | 104.9 ± 14.2 P=0.001 |
95.0 ± 15.1 P=0.001 |
78.7 ± 25.3 P=0.001 |
89.7 ± 14.4 P=0.001 |
51.2 ± 13.1 P=0.057 |
| Female | 107 ± 12 | 79 ± 10 P=0.0001 |
71 ± 11 P=0.0001 |
56 ± 16 P=0.001 |
70 ± 9 P=0.001 |
26 ± 6 P=0.001 |
| Male | 211 ± 34 | 153 ± 33 P=0.001 |
136 ± 33 P=0.0001 |
– | 130 ± 35 P=0.011 |
98 ± 30 P=0.504 |
| SAT (cm2) | 201.3 ± 13.5 | 157.6 ± 11.8 P=0.001 |
144.8 ± 12.2 P=0.001 |
125.2 ± 17.4 P=0.001 |
147.9 ± 13.4 P=0.001 |
107.4 ± 11.9 P=0.031 |
| Female | 216 ± 17 | 168 ± 13 P=0.002 |
160 ± 12 P=0.0001 |
133 ± 19 P=0.003 |
159 ± 14 P=0.0001 |
110 ± 16 P=0.034 |
| Male | 174 ± 18 | 138 ± 22 P=0.001 |
120 ± 25 P=0.001 |
– | 127 ± 29 P=0.005 |
102 ± 18 P=0.502 |
Mean ± SEM. Number stated is for the whole cohort of 13 female and 7 male participants. Male data are not shown for 24 weeks (third cycle) as n=3. The P-values for each time point vs. baseline are shown. For the control data, P refers to comparison with 52 week time point (P4).