Table 3. Fully Adjusted Model of Risks of Hospitalization, ICU Admission, and Mortality in the Cancer Subcohort.
| Variable | Adjusted hazard ratio (95% CI) | ||
|---|---|---|---|
| 14-d hospitalization | 21-d ICU admission | 28-d mortality | |
| Hematologic malignant neoplasms (vs solid tumors) | 1.57 (1.38-1.78) | 1.22 (0.95-1.55) | 1.65 (1.37-1.98) |
| COVID-19 vaccination status, No. of doses received | |||
| 0 | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 1 | 0.81(0.67-0.99) | 1.03 (0.70-1.51) | 0.51 (0.36-0.73) |
| ≥2 | 0.58 (0.44-0.76) | 0.98 (0.57-1.68) | 0.51 (0.33-0.76) |
| Age, per 1-y increase | 1.05 (1.04-1.05) | 0.98 (0.98-0.99) | 1.07 (1.06-1.07) |
| Male sex (vs female) | 1.36 (1.22-1.52) | 1.47 (1.17-1.84) | 1.61 (1.37-1.88) |
| LTC | 0.33 (0.26-0.43) | 0.59 (0.31-1.13) | 1.09 (0.88-1.34) |
| Income quintilea | |||
| 1 (lowest) | 0.97 (0.69-1.35) | 0.63 (0.31-1.25) | 1.13 (0.70-1.81) |
| 2 | 0.91 (0.69-1.20) | 0.62 (0.35-1.10) | 0.92 (0.62-1.38) |
| 3 | 1.05 (0.83-1.32) | 0.98 (0.62-1.54) | 1.05 (0.75-1.47) |
| 4 | 1.00 (0.81-1.23) | 0.86 (0.56-1.32) | 0.96 (0.70-1.33) |
| 5 (highest) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| Instability quintilea | |||
| 1 (lowest) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 2 | 0.99 (0.82-1.21) | 1.02 (0.70-1.48) | 1.08 (0.78-1.49) |
| 3 | 1.06 (0.87-1.29) | 0.90 (0.61-1.34) | 1.00 (0.72-1.39) |
| 4 | 1.05 (0.85-1.30) | 0.83 (0.55-1.26) | 1.25 (0.89-1.74) |
| 5 (highest) | 1.04 (0.83-1.30) | 1.20 (0.78-1.85) | 1.39 (0.98-1.97) |
| Deprivation quintilea | |||
| 1 (lowest) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 2 | 1.00 (0.82-1.22) | 0.88 (0.59-1.31) | 0.84 (0.63-1.13) |
| 3 | 1.04 (0.84-1.29) | 1.12 (0.72-1.75) | 1.01 (0.75-1.38) |
| 4 | 1.16 (0.92-1.47) | 1.18 (0.73-1.92) | 1.08 (0.77-1.50) |
| 5 (highest) | 1.19 (0.92-1.55) | 1.21 (0.70-2.10) | 1.09 (0.75-1.58) |
| Dependency quintilea | |||
| 1 (lowest) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 2 | 1.06 (0.90-1.25) | 1.02 (0.74-1.40) | 0.99 (0.75-1.30) |
| 3 | 1.04 (0.87-1.24) | 1.02 (0.73-1.44) | 1.16 (0.88-1.52) |
| 4 | 0.93 (0.78-1.12) | 0.77 (0.53-1.18) | 0.97 (0.73-1.28) |
| 5 (highest) | 0.82 (0.68-0.99) | 0.77 (0.52-1.14) | 0.84 (0.64-1.11) |
| Ethnic diversity quintilea | |||
| 1 (lowest) | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 2 | 0.89 (0.69-1.15) | 1.00 (0.61-1.66) | 0.93 (0.68-1.29) |
| 3 | 1.10 (0.86-1.40) | 1.40 (0.86-2.28) | 1.01 (0.74-1.38) |
| 4 | 1.09 (0.85-1.40) | 1.11 (0.68-1.82) | 0.85 (0.61-1.19) |
| 5 (highest) | 1.14 (0.88-1.49) | 1.27 (0.75-2.14) | 0.76 (0.53-1.09) |
| Public health region | |||
| Central East | 1.00 (0.69-1.47) | 1.57 (0.78-3.16) | 1.05 (0.62-1.80) |
| Central West | 1.02 (0.81-1.28) | 1.51 (0.97-2.37) | 0.88 (0.62-1.24) |
| Durham | 0.84 (0.60-1.17) | 1.78 (0.96-3.33) | 0.89 (0.54-1.45) |
| Eastern | 1.06 (0.69-1.63) | 3.20 (1.60-6.38) | 0.79 (0.43-1.46) |
| North | 1.02 (0.66-1.57) | 1.65 (0.71-3.87) | 1.11 (0.63-1.98) |
| Ottawa | 0.81 (0.59-1.13) | 1.29 (0.68-2.48) | 0.85 (0.54-1.32) |
| Peel | 0.86 (0.69-1.08) | 0.97 (0.61-1.56) | 0.89 (0.62-1.27) |
| Southwest | 0.92 (0.70-1.20) | 1.26 (0.72-2.18) | 0.79 (0.47-1.05) |
| Toronto | 1.04 (0.84-1.28) | 1.04 (0.67-1.60) | 0.86 (0.62-1.18) |
| York | 1 [Reference] | 1 [Reference] | 1 [Reference] |
Abbreviations: ICU, intensive care unit; LTC, long-term care facility.
Income quintiles measure median neighborhood incomes. Dependency quintiles measure the area-level concentration of people who do not have income from employment. Ethnic diversity quintiles measure area-level concentrations of recent immigrants and people belonging to a visible minority group (ie, persons, other than aboriginal people, who are non-Canadian in ethnicity or non-White in race). Instability quintile measures area-level concentration of people who experience high rates of family or housing instability. Deprivation quintiles measure the inability of persons and communities to access and attain basic material needs (eg, educational attainment, quality of housing).