Table 3. Assessment of behavioral functions in rat after Au-NPs administration.
| Group parameters | Control | Au-NPs 50 | Au-NPs 25 | P-value# | ||||
|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | |||
| NBT | Foot slips (No) | 0.00 | 0.000 | 0.00 | 0.000 | 0.00 | 0.000 | – |
| Time to cross (s) | 6.33 | 2.944 | 6.67 | 1.366 | 4.50 | 2.036 | 0.139 | |
| Score | 1.00 | 0.000 | 1.00 | 0.000 | 1.00 | 0.000 | ||
| OFT | Immobility (s) | 124.17 | 85.815 | 244.00 | 62.161 | 174.33 | 35.674 | 0.019* |
| Central preference (s) | 2.83 | 3.601 | 4.67 | 5.955 | 10.17 | 6.398 | 0.114 | |
| Supported rearing (No) | 6.00 | 2.828 | 1.67 | 1.366 | 8.17 | 5.382 | 0.021* | |
| Grooming (No) | 3.50 | 2.429 | 1.33 | .816 | 2.83 | 1.602 | 0.122 | |
Au-NP50, gold nanoparticles 50 ppm for 5 days; Au-NPs25, 25 ppm Au-NPs for 10 days; NBT, narrow (balance) beam test; OFT, open field test; #, ANOVA test; *P<0.05.