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The performance of UterCAD for EC early detection at different cutoffs.
| AUC (95% CI) | Cutoff | TN | TP | FN | FP | PPV | NPV | Specificity | Sensitivity | Accuracy | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UterCAD | 2 | 9 | 27 | 3 | 5 | 84.4% | 75.0% | 64.3% | 90.0% | 81.8% | |
| CHR1-22 | 0.91 (0.83–0.99) | 2.3 | 13 | 25 | 5 | 1 | 96.2% | 72.2% | 92.9% | 83.3% | 86.4% |
| 3 | 14 | 22 | 8 | 0 | 100.0% | 63.6% | 100.0% | 73.3% | 81.8% |
TN: true negative; TP: true positive; FN: false negative; FP: false true positive; PPV: positive predictive value; NPV: negative predictive value; CHR: chromosome.
