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. 2023 Aug 19;66:102856. doi: 10.1016/j.redox.2023.102856

Table 1.

Synergy scores for CP-8 and CP-23 with individual PARPi generated with the HSA method.

Drug Combination Synergy Score Most Synergistic Area Metho
Olaparib + CP-8 8.44 16.59 HSA
Niraparib + CP-8 5.36 10.05 HSA
Talazoparib + CP-8 4.39 11.41 HSA
Olaparib + CP-23 5.23 9.98 HSA
Niraparib + CP-23 1.3 5.28 HSA
Talazoparib + CP-23 5.06 9.44 HSA